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Letteria Minutoli Selected Research

flavocoxid

2/2022Reduction of oxidative stress blunts the NLRP3 inflammatory cascade in LPS stimulated human gingival fibroblasts and oral mucosal epithelial cells.
1/2019Exploiting Curcumin Synergy With Natural Products Using Quantitative Analysis of Dose-Effect Relationships in an Experimental In Vitro Model of Osteoarthritis.
1/2018Flavocoxid exerts a potent antiviral effect against hepatitis B virus.
5/2017Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice.
10/2016Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.
2/2012Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis.

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Letteria Minutoli Research Topics

Disease

17Wounds and Injuries (Trauma)
02/2018 - 09/2004
11Ischemia
12/2015 - 10/2005
10Reperfusion Injury
01/2016 - 08/2003
9Inflammation (Inflammations)
04/2022 - 01/2013
9Shock
04/2012 - 06/2002
9Ischemic Stroke
04/2012 - 03/2006
7Brain Ischemia (Cerebral Ischemia)
04/2012 - 03/2006
6Varicocele
02/2021 - 03/2011
6Necrosis
03/2017 - 03/2006
5Stroke (Strokes)
11/2011 - 05/2006
4Neoplasms (Cancer)
11/2021 - 06/2016
4Male Infertility (Male Sterility)
02/2021 - 11/2015
4Hyperplasia
01/2021 - 02/2003
4Traumatic Brain Injuries (Traumatic Brain Injury)
08/2020 - 03/2012
4Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
03/2017 - 10/2011
4Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2017 - 03/2009
4Burns
01/2015 - 07/2005
4Myocardial Ischemia (Ischemic Heart Diseases)
04/2012 - 08/2003
4Hypotension (Low Blood Pressure)
07/2008 - 06/2002
3Edema (Dropsy)
01/2018 - 07/2008
3Insulin Resistance
01/2017 - 08/2007
3Brain Injuries (Brain Injury)
06/2015 - 01/2004
3Sepsis (Septicemia)
01/2015 - 02/2012
3Pancreatitis
05/2011 - 12/2003
3Spermatic Cord Torsion (Testicular Torsion)
04/2009 - 10/2006
3Septic Shock (Toxic Shock Syndrome)
07/2008 - 06/2002
3Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
11/2007 - 03/2006
2Fuchs' Endothelial Dystrophy
04/2022 - 02/2021
2Stomatitis
02/2022 - 06/2021
2Neuroinflammatory Diseases
08/2021 - 08/2020
2Obesity
07/2021 - 08/2020
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
10/2020 - 10/2016
2Colitis
10/2020 - 10/2016
2Weight Loss (Weight Reduction)
08/2020 - 10/2016
2Psoriasis (Pustulosis Palmaris et Plantaris)
02/2020 - 03/2017
2Arthritis (Polyarthritis)
01/2019 - 11/2011
2Brain Edema (Cerebral Edema)
01/2018 - 06/2015
2Osteoporosis
02/2017 - 06/2009

Drug/Important Bio-Agent (IBA)

25Proteins (Proteins, Gene)FDA Link
01/2018 - 06/2002
17salicylhydroxamic acid (SHAM)IBA
01/2021 - 01/2003
17Messenger RNA (mRNA)IBA
05/2020 - 06/2002
14Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2018 - 09/2004
12Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2015 - 06/2002
12MelanocortinsIBA
04/2012 - 11/2005
11GenisteinIBA
03/2017 - 08/2007
11NF-kappa B (NF-kB)IBA
02/2009 - 06/2002
10PolydeoxyribonucleotidesIBA
04/2022 - 05/2008
7InflammasomesIBA
01/2021 - 12/2015
7Phosphotransferases (Kinase)IBA
01/2018 - 02/2005
7Peptides (Polypeptides)IBA
04/2012 - 11/2005
6flavocoxidIBA
02/2022 - 02/2012
6Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2015 - 11/2005
5Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
04/2022 - 03/2011
5AntioxidantsIBA
02/2022 - 06/2002
5Purinergic P1 Receptors (Adenosine Receptor)IBA
07/2021 - 10/2009
5SeleniumIBA
01/2021 - 03/2013
5LycopeneIBA
05/2020 - 10/2011
5LipopolysaccharidesIBA
01/2019 - 06/2002
5NF-KappaB Inhibitor alphaIBA
07/2008 - 01/2003
4caryophylleneIBA
11/2021 - 01/2019
4CateninsIBA
11/2021 - 01/2018
4Testosterone (Sustanon)FDA Link
01/2021 - 10/2011
4Malondialdehyde (Propanedial)IBA
05/2020 - 11/2015
4Melanocyte-Stimulating Hormones (MSH)IBA
04/2012 - 02/2011
4Neuroprotective AgentsIBA
03/2012 - 03/2006
4Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2012 - 04/2006
4alpha-MSHIBA
08/2009 - 03/2006
4Mitogen-Activated Protein Kinase 3IBA
02/2009 - 10/2004
4JNK Mitogen-Activated Protein KinasesIBA
07/2007 - 10/2004
4Mitogen-Activated Protein KinasesIBA
07/2007 - 02/2005
3Peroxisome Proliferator-Activated Receptors (PPAR)IBA
02/2021 - 04/2009
3CadmiumIBA
01/2021 - 11/2015
3IsoflavonesIBA
02/2017 - 08/2007
3DystrophinIBA
09/2015 - 03/2006
33,7-dimethyl-1-propargylxanthineIBA
01/2015 - 11/2011
3Interleukin-10 (Interleukin 10)IBA
03/2012 - 02/2011
3Interleukin-6 (Interleukin 6)IBA
03/2012 - 04/2009
3Cholinergic Agents (Cholinergics)IBA
10/2011 - 11/2005
3Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
10/2011 - 03/2006
3CeruletideIBA
05/2011 - 12/2003
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
07/2008 - 07/2005
3Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
08/2007 - 08/2003
3IRFI 042IBA
03/2006 - 06/2002
2Cannabinoid Receptors (Cannabinoid Receptor)IBA
11/2021 - 01/2019
2Pharmaceutical PreparationsIBA
07/2021 - 06/2016
2dinitrobenzenesulfonic acidIBA
10/2020 - 10/2016
2PolynucleotidesIBA
10/2020 - 01/2013
22,4-dinitrofluorobenzene sulfonic acidIBA
10/2020 - 10/2016
2Biomarkers (Surrogate Marker)IBA
08/2020 - 08/2013
2Carotenoids (Carotene)IBA
05/2020 - 10/2011
2Imiquimod (Aldara)FDA LinkGeneric
02/2020 - 03/2017
2Biological ProductsIBA
02/2020 - 06/2016
2Petrolatum (Vaseline)FDA Link
02/2020 - 03/2017
2NitratesIBA
02/2018 - 06/2008
2NitritesIBA
02/2018 - 07/2005
2Cadmium Chloride (Cadmium Dichloride)IBA
01/2018 - 11/2015
2SurvivinIBA
03/2017 - 01/2015

Therapy/Procedure

3Treatment Delay
08/2009 - 03/2006
2Corneal Transplantation (Keratoplasty)
04/2022 - 02/2021
2Drug Therapy (Chemotherapy)
06/2021 - 06/2016